For over 80 years, the National Society of Professional Engineers (NSPE) has been a leader in the promotion of ethical practice within the field of engineering. One of the Society's greatest contributions is the formation and adoption of the NSPE Code of Ethics. But the code, with its six "Fundamental Canons," is only truly instructive if engineers can bridge the gap between principles and action. Here there is no substitute for personal reflection on the ethical and philosophical issues that underlie the code. If done well, such reflection provides an indispensable basis for moral problem solving. Beyond the Code: A Philosophical Guide to Engineering Ethics is designed to complement the NSPE Code of Ethics by helping readers "go beyond" in their understanding of the philosophical issues bound up in the code. Each chapter addresses one of the Fundamental Canons of the NSPE code, and provides a philosophical analysis of the various parts of each canon by employing contemporary and classical texts. This unique approach to engineering ethics guides students and professionals in their readings of the appended selections to refine their understanding of the code in order to apply it to the practical challenges of today's engineers. Key Features: Is the first introduction to engineering ethics that helps students understand and apply the NSPE Code of Ethics to engineering practice Includes a Preface from Arthur E. Schwartz, NSPE Deputy Executive Director and General Counsel, and NAFE Executive Director As a hybrid text, includes primary philosophical texts with extensive introductions and guided reading questions from the book's three authors Offers case studies from the NSPE Board of Ethical Review, allowing students to see a direct connection between the issues discussed in the text and real-world engineering practice Includes the following pedagogical aids: "Key Terms and Concepts" for each chapter "Preparing to Read" sections before each primary source reading "Guided Reading Questions" after each primary source reading "Going Beyond-Our Questions for a Deep Dive" after each case study.

For over 80 years, the National Society of Professional Engineers (NSPE) has been a leader in the promotion of ethical practice within the field of engineering. One of the Society's greatest contributions is the formation and adoption of the NSPE Code of Ethics. But the code, with its six "Fundamental Canons," is only truly instructive if engineers can bridge the gap between principles and action. Here there is no substitute for personal reflection on the ethical and philosophical issues that underlie the code. If done well, such reflection provides an indispensable basis for moral problem solving. Beyond the Code: A Philosophical Guide to Engineering Ethics is designed to complement the NSPE Code of Ethics by helping readers "go beyond" in their understanding of the philosophical issues bound up in the code. Each chapter addresses one of the Fundamental Canons of the NSPE code, and provides a philosophical analysis of the various parts of each canon by employing contemporary and classical texts. This unique approach to engineering ethics guides students and professionals in their readings of the appended selections to refine their understanding of the code in order to apply it to the practical challenges of today's engineers. Key Features: Is the first introduction to engineering ethics that helps students understand and apply the NSPE Code of Ethics to engineering practice Includes a Preface from Arthur E. Schwartz, NSPE Deputy Executive Director and General Counsel, and NAFE Executive Director As a hybrid text, includes primary philosophical texts with extensive introductions and guided reading questions from the book's three authors Offers case studies from the NSPE Board of Ethical Review, allowing students to see a direct connection between the issues discussed in the text and real-world engineering practice Includes the following pedagogical aids: "Key Terms and Concepts" for each chapter "Preparing to Read" sections before each primary source reading "Guided Reading Questions" after each primary source reading "Going Beyond-Our Questions for a Deep Dive" after each case study.

In this book, Nigeria, the most populous country in Africa and a region in the lowest income group per capita, is used to demonstrate the potential for healthcare reorganization and collaboration with the introduction of "successful" technologies centered around available, bio-compatible, and sustainable natural resources. Our book discusses three of the top killers of children under 5 years of age in Nigeria, pneumonia (20%), diarrheal diseases (15%), and traumatic injuries (4%). These conditions are used as examples to demonstrate the potential for improved pediatric outcomes with treatments engineered from sustainable and natural resources. Furthermore, this book outlines possible action items that can help drive economic growth, educational opportunities, collaborative outreach, and workforce productivity to build a healthy and sustainable community. Medical technology in the industrialized world has seen rapid advancements leading to increased survival and greater patient outcomes. However, the development and implementation of these resources is not always applicable to regions in need of new and more basic ways to provide treatment. Moore's Law, a paradigm that considers advancement synonymous with increased digitization and optimization of electronic processes, defines the history of technology. However, the functionality of advanced and "smart" technology is essentially useless in underdeveloped areas. These regions lack some of the basic requirements for innovative medical technologies to impact human health, such as electricity, access to spare parts, computer analysis tools, and network architecture. In addition, the poor physical infrastructure, insufficient management, and lack of technical culture are barriers for entry and sustainability of these technologies. Rather than importing medical devices from industrialized countries, we propose that the mindset and research focus for under developed areas must be on "successful" technologies. Simply put, these areas need technology that "gets the job done."

Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on "Engineering Concepts" reviews the relevant fundamental principles that guide rational design. The following section on "Materials Design" discusses how the design process applies engineering concepts for use in physiological systems. A third section on "Implementation" discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on "Clinical Applications" which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. * Provides a comprehensive description of drug delivery systems from a materials perspective * Includes a wide-ranging discussion of clinical applications of drug delivery systems * Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. * Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type

This book investigates the potential medical benefits natural biomaterials can offer in developing countries by analyzing the case of Bolivia. The book explores the medical and health related applications of Bolivian commodities: quinoa, barley, sugarcane, corn, sorghum and sunflower seeds. This book helps readers better understand some of the key health concerns facing countries like Bolivia and how naturally derived biomaterials and therapeutics could help substantially alleviate many of their problems.

Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on "Engineering Concepts" reviews the relevant fundamental principles that guide rational design. The following section on "Materials Design" discusses how the design process applies engineering concepts for use in physiological systems. A third section on "Implementation" discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on "Clinical Applications" which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. * Provides a comprehensive description of drug delivery systems from a materials perspective * Includes a wide-ranging discussion of clinical applications of drug delivery systems * Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. * Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type

Biomaterials for Clinical Applications is organized according to the World Health Organization's report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering.

Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.

This book advances biomedical innovations to address the plethora of health problems afflicting the developing world. A panoply of cultural, economic, infrastructural, and other factors prevent many interventions currently popular in the developed world from being similarly effective in the developing world. This book discusses less-traditional approaches, such as naturally based biomaterials and therapeutics, an area that has traditionally been overlooked but has also demonstrated impressive potential for health applications in recent years. This book explores precisely the kinds of applications which can enable countries like India to access more effective, inexpensive treatments while also taking more ownership of their healthcare technologies and innovations.

This book focuses on the adoption of medical technology in the developing world, and the role that can be played by new biomaterials. These authors urge that advanced technology be aligned with the needs of developing and emerging markets, and an alternative definition of technology be embraced. This "new technology" considers natural sources of materials and tools for treatment and is not restricted to the usual traditional computerized or electronic technology. This book explores the difficulties that accompany successful transfer of technologies between disparate settings. The book then leaves the world of traditional technology and focuses on biomaterials, which represent an enormous opportunity for developing societies to become active participants in the development of new technologies. Biomaterials can be used in the treatment of disease throughout the developing world and beyond. Biomaterials encompass a range of naturally derived substances; of particular interest here are naturally derived and synthetically manufactured materials with potential applications in different body systems. Because many of these materials can be grown, the agricultural output of developing nations is an obvious potential source of these biomaterials. The book considers the cases of Ghana and Nicaragua as examples of the broader situation in West Africa and Central/South America. These two regions are uniquely positioned with regard to both health care and technological capabilities, and both stand to grow significantly in the coming years. While the agricultural sectors of the two nations are quite different, both are major producers of corn and other materials that should be investigated further. Of course, the difficulty in using a foodstuff for medical purposes is fully explored.

Biomaterials for Clinical Applications is organized according to the World Health Organization 's report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering.

Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.

Throughout history, humanity has been plagued by a myriad of humanitarian crises that seemingly take the form of perpetual human suffering. Today, approximately 125,000,000 people require humanitarian assistance as the result of famine, war, geopolitical conflict, and natural disasters. A core component of this suffering is afflictions related to human health, where disturbances strain or overwhelm the existing healthcare infrastructure to create the conditions for an increase in morbidities and co-morbidities. One of the more startling elements is the loss of life to preventable medical conditions that were not properly treated or even diagnosed in the field, and is often due to the limited interventional capacity that medical teams and humanitarian practitioners have in these scenarios. These individuals are often hindered by medical equipment deficiencies or devices not meant to function in austere conditions. The development of highly versatile, feasible, and cost-effective medical devices and technologies that can be deployed in the field is essential to enhancing medical care in unconventional settings. In this book we examine the nature of the creative problem-solving paradigm, and dissect the intersection of frugal, disruptive, open, and reverse innovation processes in advancing humanitarian medicine. Specifically, we examine the feasible deployment of these devices and technologies in unconventional environments not only by humanitarian aid and disaster relief agencies, but also by crisis-affected communities themselves. The challenge is complex, but the financial support and technical development of innovative solutions for the delivery of humanitarian aid is a process in which everyone is a stakeholder.

This book examines the potential to deploy low-cost, three-dimensional printers known as RepRaps in developing countries to fabricate surgical instruments and medical supplies to combat the "global surgical burden of disease." Approximately two billion people in developing countries around the world lack access to essential surgical services, resulting in the avoidable deaths of millions of individuals each year. A fundamental barrier that inhibits access to surgical care in these locations is the lack of basic surgical instruments and supplies in healthcare facilities. RepRap printers are highly versatile 3D printers assembled from basic, domestically sourced materials that can fabricate low-cost surgical instruments on-site, ultimately enhancing the interventional capacity of healthcare facilities to treat patients. Rather than focusing on one specific field of interest, this book takes an integrative approach that incorporates topics and methods from multiple disciplines ranging from global health and development economics to materials science and applied engineering. These topics include the feasibility of using bio-based plastics to fabricate surgical instruments via 3D printing sustainably, the application of "frugal innovation and engineering" in resource-poor settings, and analyses related to the social returns on investment, barriers to entry, and current and future medical device supply-chain paradigms. In taking a multi-disciplinary approach, the reader can gain a holistic understanding of the multiple facets related to implementing medical device innovations in developing countries.